3bg8
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3bg8| PDB=3bg8 | SCENE= }} | {{STRUCTURE_3bg8| PDB=3bg8 | SCENE= }} | ||
===Crystal structure of Factor XIa in complex with Clavatadine A=== | ===Crystal structure of Factor XIa in complex with Clavatadine A=== | ||
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{{ABSTRACT_PUBMED_18510371}} | {{ABSTRACT_PUBMED_18510371}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]], Factor XI deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3bg8]] is a 1 chain structure of [[Factor XIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG8 OCA]. | |
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+ | ==See Also== | ||
+ | *[[Factor XIa|Factor XIa]] | ||
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:018510371</ref><references group="xtra"/> | |
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Oster, L.]] | [[Category: Oster, L.]] | ||
[[Category: Xue, Y.]] | [[Category: Xue, Y.]] | ||
- | [[Category: Alternative splicing]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Covalent inhibitor]] | [[Category: Covalent inhibitor]] | ||
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[[Category: Heparin-binding]] | [[Category: Heparin-binding]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:00:18 2008'' |
Revision as of 06:31, 26 July 2012
Contents |
Crystal structure of Factor XIa in complex with Clavatadine A
Template:ABSTRACT PUBMED 18510371
About this Structure
3bg8 is a 1 chain structure of Factor XIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Buchanan MS, Carroll AR, Wessling D, Jobling M, Avery VM, Davis RA, Feng Y, Xue Y, Oster L, Fex T, Deinum J, Hooper JN, Quinn RJ. Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa. J Med Chem. 2008 Jun 26;51(12):3583-7. PMID:18510371 doi:10.1021/jm800314b