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1d96

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(New page: 200px<br /><applet load="1d96" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d96, resolution 2.000&Aring;" /> '''MOLECULAR STRUCTURE...)
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[[Image:1d96.gif|left|200px]]<br /><applet load="1d96" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1d96, resolution 2.000&Aring;" />
caption="1d96, resolution 2.000&Aring;" />
'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''<br />
'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''<br />
==Overview==
==Overview==
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The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA, hybrid segments surrounding a central region of double helical DNA; its, molecular structure has been solved by X-ray analysis. All three parts of, the molecule adopt a conformation which is close to that seen in the, 11-fold RNA double helix. The conformation of the ribonucleotides is, partly determined by water molecules bridging between the ribose O2', hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no, structural discontinuities. However, the central DNA TATA sequence has, some structural irregularities.
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The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.
==About this Structure==
==About this Structure==
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1D96 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].
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1D96 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].
==Reference==
==Reference==
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6181416 6181416]
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6181416 6181416]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: Boeckel, S.A.A.Van.]]
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[[Category: Boeckel, S A.A Van.]]
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[[Category: Boom, J.H.Van.]]
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[[Category: Boom, J H.Van.]]
[[Category: Fujii, S.]]
[[Category: Fujii, S.]]
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[[Category: Marel, G.A.Van.Der.]]
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[[Category: Marel, G A.Van Der.]]
[[Category: Rich, A.]]
[[Category: Rich, A.]]
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[[Category: Wang, A.H.J.]]
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[[Category: Wang, A H.J.]]
[[Category: a-dna/rna]]
[[Category: a-dna/rna]]
[[Category: double helix]]
[[Category: double helix]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 02:47:52 2007''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:14:14 2008''

Revision as of 10:14, 21 February 2008

Image:1d96.gif

1d96, resolution 2.000Å

Drag the structure with the mouse to rotate

MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA

Overview

The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.

About this Structure

1D96 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:6181416

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