1pwm
From Proteopedia
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===Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat=== | ===Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1pwm]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWM OCA]. | |
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| + | ==See Also== | ||
| + | *[[Aldose Reductase|Aldose Reductase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015146479</ref><ref group="xtra">PMID:018754631</ref><references group="xtra"/> |
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Atomic resolution]] | [[Category: Atomic resolution]] | ||
[[Category: Inhibitor binding]] | [[Category: Inhibitor binding]] | ||
| + | [[Category: Oxidoreductase]] | ||
[[Category: Ternary complex]] | [[Category: Ternary complex]] | ||
| - | [[Category: X-ray crystallography]] | ||
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Revision as of 06:53, 26 July 2012
Contents |
Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat
Template:ABSTRACT PUBMED 15146479
About this Structure
1pwm is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M, Joachimiak A, Schulze-Briese C, Tomizaki T, Mitschler A, Podjarny A. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins. 2004 Jun 1;55(4):805-13. PMID:15146479 doi:10.1002/prot.20001
- Chen X, Weber I, Harrison RW. Hydration water and bulk water in proteins have distinct properties in radial distributions calculated from 105 atomic resolution crystal structures. J Phys Chem B. 2008 Sep 25;112(38):12073-80. Epub 2008 Aug 28. PMID:18754631 doi:10.1021/jp802795a
Categories: Aldehyde reductase | Homo sapiens | Darmanin, C. | El-Kabbani, O. | Hazemann, I. | Joachimiak, A. | Mitschler, A. | Oka, M. | Podjarny, A. | Ruiz, F. | Schneider, T R. | Schulze-Briese, C. | Tomizaki, T. | Aldose reductase | Atomic resolution | Inhibitor binding | Oxidoreductase | Ternary complex
