1xxf
From Proteopedia
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===Crystal Structure of the FXIa Catalytic Domain in Complex with Ecotin Mutant (EcotinP)=== | ===Crystal Structure of the FXIa Catalytic Domain in Complex with Ecotin Mutant (EcotinP)=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]], Factor XI deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1xxf]] is a 4 chain structure of [[Ecotin]] and [[Factor XIa]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXF OCA]. | |
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| + | ==See Also== | ||
| + | *[[Ecotin|Ecotin]] | ||
| + | *[[Factor XIa|Factor XIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015545266</ref><references group="xtra"/> |
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Strickler, J E.]] | [[Category: Strickler, J E.]] | ||
[[Category: Weaver, D T.]] | [[Category: Weaver, D T.]] | ||
| + | [[Category: Blood clotting-hydrolase inhibitor complex]] | ||
[[Category: Catalytic domain]] | [[Category: Catalytic domain]] | ||
[[Category: Ecotin]] | [[Category: Ecotin]] | ||
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Substrate-like interaction]] | [[Category: Substrate-like interaction]] | ||
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Revision as of 07:14, 26 July 2012
Contents |
Crystal Structure of the FXIa Catalytic Domain in Complex with Ecotin Mutant (EcotinP)
Template:ABSTRACT PUBMED 15545266
About this Structure
1xxf is a 4 chain structure of Ecotin and Factor XIa with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE. Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions. J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:15545266 doi:10.1074/jbc.M411309200
Categories: Coagulation factor XIa | Escherichia coli | Homo sapiens | Abdel-Meguid, S S. | Babine, R E. | Gelfand, E. | Gorga, J C. | Jin, L. | Pandey, P. | Seidl, K J. | Strickler, J E. | Weaver, D T. | Blood clotting-hydrolase inhibitor complex | Catalytic domain | Ecotin | Fxia | Serine protease | Substrate-like interaction
