3n2v
From Proteopedia
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===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide=== | ===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide=== | ||
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{{ABSTRACT_PUBMED_20965620}} | {{ABSTRACT_PUBMED_20965620}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3n2v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2V OCA]. | + | [[3n2v]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2V OCA]. |
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| + | ==See Also== | ||
| + | *[[Elastase|Elastase]] | ||
| + | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020965620</ref><ref group="xtra">PMID:017269766</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
Revision as of 07:51, 26 July 2012
Contents |
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide
Template:ABSTRACT PUBMED 20965620
About this Structure
3n2v is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Attolino E, Calderone V, Dragoni E, Fragai M, Richichi B, Luchinat C, Nativi C. Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem. 2010 Oct 19. PMID:20965620 doi:10.1016/j.ejmech.2010.09.057
- Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
