2ghg

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Revision as of 08:01, 26 July 2012

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Template:STRUCTURE 2ghg

Contents 1 h-CHK1 complexed with A431994 2 About this Structure 3 See Also 4 Reference

h-CHK1 complexed with A431994

Template:ABSTRACT PUBMED 16644221

About this Structure

2ghg is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Serine/threonine protein kinase

Reference

• Zhu GD, Gandhi VB, Gong J, Luo Y, Liu X, Shi Y, Guan R, Magnone SR, Klinghofer V, Johnson EF, Bouska J, Shoemaker A, Oleksijew A, Jarvis K, Park C, Jong RD, Oltersdorf T, Li Q, Rosenberg SH, Giranda VL. Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3424-9. Epub 2006 Apr 27. PMID:16644221 doi:10.1016/j.bmcl.2006.04.005