2a4l
From Proteopedia
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[[Image:2a4l.png|left|200px]] | [[Image:2a4l.png|left|200px]] | ||
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{{STRUCTURE_2a4l| PDB=2a4l | SCENE= }} | {{STRUCTURE_2a4l| PDB=2a4l | SCENE= }} | ||
===Human cyclin-dependent kinase 2 in complex with roscovitine=== | ===Human cyclin-dependent kinase 2 in complex with roscovitine=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Cell Division Protein Kinase 2]] | + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009030780</ref><ref group="xtra">PMID:008610110</ref><ref group="xtra">PMID:008510751</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 08:09, 26 July 2012
Contents |
Human cyclin-dependent kinase 2 in complex with roscovitine
Template:ABSTRACT PUBMED 9030780
About this Structure
2a4l is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur J Biochem. 1997 Jan 15;243(1-2):518-26. PMID:9030780
- De Azevedo WF Jr, Mueller-Dieckmann HJ, Schulze-Gahmen U, Worland PJ, Sausville E, Kim SH. Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2735-40. PMID:8610110
- De Bondt HL, Rosenblatt J, Jancarik J, Jones HD, Morgan DO, Kim SH. Crystal structure of cyclin-dependent kinase 2. Nature. 1993 Jun 17;363(6430):595-602. PMID:8510751 doi:http://dx.doi.org/10.1038/363595a0
