3lgp
From Proteopedia
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[[Image:3lgp.png|left|200px]] | [[Image:3lgp.png|left|200px]] | ||
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{{STRUCTURE_3lgp| PDB=3lgp | SCENE= }} | {{STRUCTURE_3lgp| PDB=3lgp | SCENE= }} | ||
===Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor=== | ===Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor=== | ||
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==See Also== | ==See Also== | ||
- | *[[A Disintegrin And Metalloproteinase]] | + | *[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020638281</ref><references group="xtra"/> |
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orth, P.]] | [[Category: Orth, P.]] | ||
+ | [[Category: Cleavage on pair of basic residue]] | ||
+ | [[Category: Disulfide bond]] | ||
+ | [[Category: Glycoprotein]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Membrane]] | ||
+ | [[Category: Metal-binding]] | ||
+ | [[Category: Metalloprotease]] | ||
+ | [[Category: Notch signaling pathway]] | ||
+ | [[Category: Phosphoprotein]] | ||
+ | [[Category: Protease]] | ||
+ | [[Category: Sh3-binding]] | ||
+ | [[Category: Transmembrane]] | ||
+ | [[Category: Zymogen]] |
Revision as of 08:32, 26 July 2012
Contents |
Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor
Template:ABSTRACT PUBMED 20638281
About this Structure
3lgp is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Li D, Popovici-Muller J, Belanger DB, Caldwell J, Dai C, David M, Girijavallabhan VM, Lavey BJ, Lee JF, Liu Z, Mazzola R, Rizvi R, Rosner KE, Shankar B, Spitler J, Ting PC, Vaccaro H, Yu W, Zhou G, Zhu Z, Niu X, Sun J, Guo Z, Orth P, Chen S, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Shipps GW Jr, Siddiqui MA, Strickland CO. Structure and activity relationships of tartrate-based TACE inhibitors. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4812-5. Epub 2010 Jun 25. PMID:20638281 doi:10.1016/j.bmcl.2010.06.104