3l59
From Proteopedia
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{{STRUCTURE_3l59| PDB=3l59 | SCENE= }} | {{STRUCTURE_3l59| PDB=3l59 | SCENE= }} | ||
===Structure of BACE Bound to SCH710413=== | ===Structure of BACE Bound to SCH710413=== | ||
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{{ABSTRACT_PUBMED_20043696}} | {{ABSTRACT_PUBMED_20043696}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3l59]] is a 2 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L59 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020043696</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Strickland, C]] | [[Category: Strickland, C]] | ||
[[Category: Zhu, Z]] | [[Category: Zhu, Z]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Alzheimer]] | [[Category: Alzheimer]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:22:28 2010'' | ||
Revision as of 08:36, 26 July 2012
Contents |
Structure of BACE Bound to SCH710413
Template:ABSTRACT PUBMED 20043696
About this Structure
3l59 is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p
Categories: Homo sapiens | Memapsin 2 | Strickland, C | Zhu, Z | Alzheimer | Aspartyl protease | Bace1 | Disulfide bond | Endoplasmic reticulum | Endosome | Glycoprotein | Golgi apparatus | Hydrolase | Membrane | Protease | Transmembrane | Zymogen
