3cvk
From Proteopedia
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===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor=== | ===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3cvk]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CVK OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018722768</ref><references group="xtra"/> |
| - | [[Category: | + | [[Category: RNA-directed RNA polymerase]] |
[[Category: Viruses]] | [[Category: Viruses]] | ||
[[Category: Han, Q.]] | [[Category: Han, Q.]] | ||
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[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
[[Category: Rna-directed rna polymerase]] | [[Category: Rna-directed rna polymerase]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 08:36, 26 July 2012
Contents |
Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
Template:ABSTRACT PUBMED 18722768
About this Structure
3cvk is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Ruebsam F, Sun Z, Ayida BK, Webber SE, Zhou Y, Zhao Q, Kissinger CR, Showalter RE, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5002-5. Epub 2008 Aug 9. PMID:18722768 doi:10.1016/j.bmcl.2008.08.017
