3cvk

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Revision as of 08:36, 26 July 2012

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Template:STRUCTURE 3cvk

Contents 1 Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18722768

About this Structure

3cvk is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

• RNA polymerase

Reference

• Ruebsam F, Sun Z, Ayida BK, Webber SE, Zhou Y, Zhao Q, Kissinger CR, Showalter RE, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5002-5. Epub 2008 Aug 9. PMID:18722768 doi:10.1016/j.bmcl.2008.08.017