2vij
From Proteopedia
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===HUMAN BACE-1 IN COMPLEX WITH 3-(1,1-DIOXIDOTETRAHYDRO-2H-1, 2-THIAZIN-2-YL)-5-(ETHYLAMINO)-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHALENYLAMINO) PROPYL)BENZAMIDE=== | ===HUMAN BACE-1 IN COMPLEX WITH 3-(1,1-DIOXIDOTETRAHYDRO-2H-1, 2-THIAZIN-2-YL)-5-(ETHYLAMINO)-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHALENYLAMINO) PROPYL)BENZAMIDE=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2vij]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VIJ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018171615</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Hawkins, J.]] | [[Category: Hawkins, J.]] | ||
[[Category: Hussain, I.]] | [[Category: Hussain, I.]] | ||
| - | [[Category: Johnson, C.]] | + | [[Category: Johnson, C N.]] |
[[Category: Macpherson, D.]] | [[Category: Macpherson, D.]] | ||
[[Category: Maile, G.]] | [[Category: Maile, G.]] | ||
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[[Category: Rowland, P.]] | [[Category: Rowland, P.]] | ||
[[Category: Skidmore, J.]] | [[Category: Skidmore, J.]] | ||
| - | [[Category: Smith, K.]] | + | [[Category: Smith, K J.]] |
[[Category: Soleil, V.]] | [[Category: Soleil, V.]] | ||
[[Category: Stanway, S.]] | [[Category: Stanway, S.]] | ||
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[[Category: Ward, J.]] | [[Category: Ward, J.]] | ||
[[Category: Wayne, G.]] | [[Category: Wayne, G.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Asp-2]] | [[Category: Asp-2]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:57:43 2009'' | ||
Revision as of 08:41, 26 July 2012
Contents |
HUMAN BACE-1 IN COMPLEX WITH 3-(1,1-DIOXIDOTETRAHYDRO-2H-1, 2-THIAZIN-2-YL)-5-(ETHYLAMINO)-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHALENYLAMINO) PROPYL)BENZAMIDE
Template:ABSTRACT PUBMED 18171615
About this Structure
2vij is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Beswick P, Charrier N, Clarke B, Demont E, Dingwall C, Dunsdon R, Faller A, Gleave R, Hawkins J, Hussain I, Johnson CN, MacPherson D, Maile G, Matico R, Milner P, Mosley J, Naylor A, O'Brien A, Redshaw S, Riddell D, Rowland P, Skidmore J, Soleil V, Smith KJ, Stanway S, Stemp G, Stuart A, Sweitzer S, Theobald P, Vesey D, Walter DS, Ward J, Wayne G. BACE-1 inhibitors part 3: identification of hydroxy ethylamines (HEAs) with nanomolar potency in cells. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1022-6. Epub 2007 Dec 15. PMID:18171615 doi:10.1016/j.bmcl.2007.12.020
Categories: Homo sapiens | Memapsin 2 | Beswick, P. | Brien, A O. | Charrier, N. | Clarke, B. | Demont, E. | Dingwall, C. | Dunsdon, R. | Faller, A. | Gleave, R. | Hawkins, J. | Hussain, I. | Johnson, C N. | Macpherson, D. | Maile, G. | Matico, R. | Milner, P. | Mosley, J. | Naylor, A. | Redshaw, S. | Riddell, D. | Rowland, P. | Skidmore, J. | Smith, K J. | Soleil, V. | Stanway, S. | Stemp, G. | Stuart, A. | Sweitzer, S. | Theobald, P. | Vesey, D. | Walter, D S. | Ward, J. | Wayne, G. | Asp-2 | Aspartyl protease | Bace-1 | Beta-secretase | Beta-site app cleaving enzyme | Glycoprotein | Hydrolase | Memapsin-2 | Membrane | Protease | Transmembrane | Zymogen
