1dir
From Proteopedia
(New page: 200px<br /><applet load="1dir" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dir, resolution 2.60Å" /> '''CRYSTAL STRUCTURE OF...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1dir.gif|left|200px]]<br /><applet load="1dir" size=" | + | [[Image:1dir.gif|left|200px]]<br /><applet load="1dir" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1dir, resolution 2.60Å" /> | caption="1dir, resolution 2.60Å" /> | ||
'''CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER'''<br /> | '''CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER'''<br /> | ||
==Overview== | ==Overview== | ||
| - | A binary complex of dihydropteridine reductase and NADH crystallizes in | + | A binary complex of dihydropteridine reductase and NADH crystallizes in the space group C2, with a = 222.2, b = 46.5, c = 95.3 A and beta = 101.1 degrees. There are two dimers in the asymmetric unit. The structure was solved by molecular-replacement techniques and refined with 2.6 A data to a crystallographic R factor of 16.8%. Each dimer has twofold non-crystallographic symmetry and the four individual monomers in the asymmetric unit have the same overall molecular conformation. |
==About this Structure== | ==About this Structure== | ||
| - | 1DIR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with NAD as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34] Full crystallographic information is available from [http:// | + | 1DIR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DIR OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Matthews, D | + | [[Category: Matthews, D A.]] |
| - | [[Category: Skinner, M | + | [[Category: Skinner, M M.]] |
[[Category: Su, Y.]] | [[Category: Su, Y.]] | ||
| - | [[Category: Varughese, K | + | [[Category: Varughese, K I.]] |
| - | [[Category: Whitely, J | + | [[Category: Whitely, J M.]] |
| - | [[Category: Xuong, N | + | [[Category: Xuong, N H.]] |
[[Category: NAD]] | [[Category: NAD]] | ||
[[Category: oxidoreductase(acting on nadh or nadph)]] | [[Category: oxidoreductase(acting on nadh or nadph)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:16:57 2008'' |
Revision as of 10:17, 21 February 2008
|
CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER
Overview
A binary complex of dihydropteridine reductase and NADH crystallizes in the space group C2, with a = 222.2, b = 46.5, c = 95.3 A and beta = 101.1 degrees. There are two dimers in the asymmetric unit. The structure was solved by molecular-replacement techniques and refined with 2.6 A data to a crystallographic R factor of 16.8%. Each dimer has twofold non-crystallographic symmetry and the four individual monomers in the asymmetric unit have the same overall molecular conformation.
About this Structure
1DIR is a Single protein structure of sequence from Rattus norvegicus with as ligand. Active as 6,7-dihydropteridine reductase, with EC number 1.5.1.34 Full crystallographic information is available from OCA.
Reference
Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver., Su Y, Skinner MM, Xuong NH, Matthews DA, Whiteley JM, Varughese KI, Acta Crystallogr D Biol Crystallogr. 1994 Nov 1;50(Pt 6):884-8. PMID:15299357
Page seeded by OCA on Thu Feb 21 12:16:57 2008
