1blf
From Proteopedia
(New page: 200px<br /> <applet load="1blf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1blf, resolution 2.80Å" /> '''STRUCTURE OF DIFERR...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1BLF is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with NAG, FE and CO3 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BLF OCA]]. | + | 1BLF is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with NAG, FE and CO3 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: FE1 and FE2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BLF OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: transferrin]] | [[Category: transferrin]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:51:06 2007'' |
Revision as of 11:46, 30 October 2007
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STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION
Overview
The three-dimensional structure of diferric bovine lactoferrin (bLf) has, been determined by X-ray crystallography in order to investigate the, factors that influence iron binding and release by transferrins. The, structure was solved by molecular replacement, using the coordinates of, diferric human lactoferrin (hLf) as a search model, and was refined with, data to 2.8 A resolution by simulated annealing (X-PLOR) and restrained, least squares (TNT). The final model comprises 5310 protein atoms, (residues 5 to 689), 124 carbohydrate atoms (from ten monosaccharide, units, in three glycan chains), 2 Fe3+, 2 CO32- and 50 water molecules., This model gives an R-factor of 0.232 for 21440 reflections in the, resolution range 30.0 to 2.8 A. The folding of the bLf molecule is, essentially the ... [(full description)]
About this Structure
1BLF is a [Single protein] structure of sequence from [Bos taurus] with NAG, FE and CO3 as [ligands]. Structure known Active Sites: FE1 and FE2. Full crystallographic information is available from [OCA].
Reference
Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution., Moore SA, Anderson BF, Groom CR, Haridas M, Baker EN, J Mol Biol. 1997 Nov 28;274(2):222-36. PMID:9398529
Page seeded by OCA on Tue Oct 30 13:51:06 2007
Categories: Bos taurus | Single protein | Anderson, B.F. | Baker, E.N. | Groom, C.R. | Haridas, M. | Moore, S.A. | CO3 | FE | NAG | Carbohydrate structure | Iron-binding protein | Lactoferrin | Transferrin
