1gjb
From Proteopedia
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{{STRUCTURE_1gjb| PDB=1gjb | SCENE= }} | {{STRUCTURE_1gjb| PDB=1gjb | SCENE= }} | ||
===ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS=== | ===ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1gjb]] is a 2 chain structure of [[Urokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJB OCA]. | |
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| + | ==See Also== | ||
| + | *[[Urokinase|Urokinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011731301</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: U-plasminogen activator]] | [[Category: U-plasminogen activator]] | ||
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[[Category: Sprengeler, P A.]] | [[Category: Sprengeler, P A.]] | ||
[[Category: Verner, E.]] | [[Category: Verner, E.]] | ||
| + | [[Category: Blood clotting]] | ||
[[Category: H2o displacement]] | [[Category: H2o displacement]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Selectivity at s1]] | [[Category: Selectivity at s1]] | ||
[[Category: Ser190/ala190 protease]] | [[Category: Ser190/ala190 protease]] | ||
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[[Category: Tpa]] | [[Category: Tpa]] | ||
[[Category: Upa]] | [[Category: Upa]] | ||
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Revision as of 08:54, 26 July 2012
Contents |
ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS
Template:ABSTRACT PUBMED 11731301
About this Structure
1gjb is a 2 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301
Categories: Homo sapiens | U-plasminogen activator | Allen, D. | Breitenbucher, J G. | Hui, H. | Katz, B A. | Luong, C. | Mackman, R L. | Martelli, A. | McGee, D. | Spencer, J R. | Sprengeler, P A. | Verner, E. | Blood clotting | H2o displacement | Hydrolase | Selectivity at s1 | Ser190/ala190 protease | Structure-based drug design | Tpa | Upa
