2xjx
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
[[Image:2xjx.png|left|200px]] | [[Image:2xjx.png|left|200px]] | ||
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_2xjx", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_2xjx| PDB=2xjx | SCENE= }} | {{STRUCTURE_2xjx| PDB=2xjx | SCENE= }} | ||
===STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND=== | ===STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND=== | ||
- | |||
- | <!-- | ||
- | The line below this paragraph, {{ABSTRACT_PUBMED_20662534}}, adds the Publication Abstract to the page | ||
- | (as it appears on PubMed at http://www.pubmed.gov), where 20662534 is the PubMed ID number. | ||
- | --> | ||
{{ABSTRACT_PUBMED_20662534}} | {{ABSTRACT_PUBMED_20662534}} | ||
Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
- | *[[Heat Shock Proteins]] | + | *[[Heat Shock Proteins|Heat Shock Proteins]] |
==Reference== | ==Reference== |
Revision as of 09:12, 26 July 2012
Contents |
STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND
Template:ABSTRACT PUBMED 20662534
About this Structure
2xjx is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-di hydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design. J Med Chem. 2010 Jul 28. PMID:20662534 doi:10.1021/jm100060b
Categories: Homo sapiens | Callaghan, O. | Carr, M G. | Chessari, G. | Congreve, M. | Cowan, S. | Coyle, J E. | Downham, R. | Figueroa, E. | Frederickson, M. | Graham, B. | Mcmenamin, R. | Murray, C W. | Obrien, M A. | Patel, S. | Phillips, T R. | Williams, G. | Woodhead, A J. | Woolford, A J.A. | Atp binding domain | Chaperone | Stress response