2xjg
From Proteopedia
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{{STRUCTURE_2xjg| PDB=2xjg | SCENE= }} | {{STRUCTURE_2xjg| PDB=2xjg | SCENE= }} | ||
===Structure of HSP90 with small molecule inhibitor bound=== | ===Structure of HSP90 with small molecule inhibitor bound=== | ||
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Revision as of 09:13, 26 July 2012
Contents |
Structure of HSP90 with small molecule inhibitor bound
Template:ABSTRACT PUBMED 20662534
About this Structure
2xjg is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-di hydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design. J Med Chem. 2010 Jul 28. PMID:20662534 doi:10.1021/jm100060b
Categories: Homo sapiens | Callaghan, O. | Carr, M G. | Chessari, G. | Congreve, M. | Cowan, S. | Coyle, J E. | Downham, R. | Figueroa, E. | Frederickson, M. | Graham, B. | Mcmenamin, R. | Murray, C W. | Obrien, M A. | Patel, S. | Phillips, T R. | Williams, B. | Woodhead, A J. | Woolford, A J.A. | Atp binding domain | Chaperone | Stress response
