1bli
From Proteopedia
(New page: 200px<br /> <applet load="1bli" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bli, resolution 1.90Å" /> '''BACILLUS LICHENIFOR...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1BLI is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]] with CA and NA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BLI OCA]]. | + | 1BLI is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]] with CA and NA as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]]. Structure known Active Sites: CA1, CA2, CA3, CS and NA1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BLI OCA]]. |
==Reference== | ==Reference== | ||
Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad., Machius M, Declerck N, Huber R, Wiegand G, Structure. 1998 Mar 15;6(3):281-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9551551 9551551] | Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad., Machius M, Declerck N, Huber R, Wiegand G, Structure. 1998 Mar 15;6(3):281-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9551551 9551551] | ||
| + | [[Category: Alpha-amylase]] | ||
[[Category: Bacillus licheniformis]] | [[Category: Bacillus licheniformis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: thermostability]] | [[Category: thermostability]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:51:23 2007'' |
Revision as of 11:46, 30 October 2007
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BACILLUS LICHENIFORMIS ALPHA-AMYLASE
Overview
BACKGROUND: The structural basis as to how metals regulate the functional, state of a protein by altering or stabilizing its conformation has been, characterized in relatively few cases because the metal-free form of the, protein is often partially disordered and unsuitable for crystallographic, analysis. This is not the case, however, for Bacillus licheniformis, alpha-amylase (BLA) for which the structure of the metal-free form is, available. BLA is a hyperthermostable enzyme which is widely used in, biotechnology, for example in the breakdown of starch or as a component of, detergents. The determination of the structure of BLA in the, metal-containing form, together with comparisons to the apo enzyme, will, help us to understand the way in which metal ions can regulate enzyme, activity. ... [(full description)]
About this Structure
1BLI is a [Single protein] structure of sequence from [Bacillus licheniformis] with CA and NA as [ligands]. Active as [Alpha-amylase], with EC number [3.2.1.1]. Structure known Active Sites: CA1, CA2, CA3, CS and NA1. Full crystallographic information is available from [OCA].
Reference
Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad., Machius M, Declerck N, Huber R, Wiegand G, Structure. 1998 Mar 15;6(3):281-92. PMID:9551551
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