3l8x
From Proteopedia
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{{STRUCTURE_3l8x| PDB=3l8x | SCENE= }} | {{STRUCTURE_3l8x| PDB=3l8x | SCENE= }} | ||
===P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor=== | ===P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor=== | ||
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{{ABSTRACT_PUBMED_18359226}} | {{ABSTRACT_PUBMED_18359226}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3l8x]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3cg2 3cg2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8X OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018359226</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
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[[Category: Serine/threonine-protine kinase]] | [[Category: Serine/threonine-protine kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 09:23, 26 July 2012
Contents |
P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor
Template:ABSTRACT PUBMED 18359226
About this Structure
3l8x is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3cg2. Full crystallographic information is available from OCA.
See Also
Reference
- Das J, Moquin RV, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2652-7. Epub 2008 Mar 10. PMID:18359226 doi:10.1016/j.bmcl.2008.03.019
