3bsc
From Proteopedia
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{{STRUCTURE_3bsc| PDB=3bsc | SCENE= }} | {{STRUCTURE_3bsc| PDB=3bsc | SCENE= }} | ||
===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor=== | ===Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor=== | ||
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{{ABSTRACT_PUBMED_18242088}} | {{ABSTRACT_PUBMED_18242088}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3bsc]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSC OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:018242088</ref><references group="xtra"/> | |
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Viruses]] | [[Category: Viruses]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:29:20 2008'' | ||
Revision as of 09:24, 26 July 2012
Contents |
Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor
Template:ABSTRACT PUBMED 18242088
About this Structure
3bsc is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088 doi:S0960-894X(08)00010-3
