3hyg
From Proteopedia
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m (Protected "3hyg" [edit=sysop:move=sysop]) |
Revision as of 10:12, 26 July 2012
Contents |
Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound
Template:ABSTRACT PUBMED 19586907
About this Structure
3hyg is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tortorella MD, Tomasselli AG, Mathis KJ, Schnute ME, Woodard SS, Munie G, Williams JM, Caspers N, Wittwer AJ, Malfait AM, Shieh HS. Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors. J Biol Chem. 2009 Sep 4;284(36):24185-91. Epub 2009 Jul 8. PMID:19586907 doi:10.1074/jbc.M109.029116
Categories: Homo sapiens | Caspers, N. | Mathis, K J. | Shieh, H S. | Tomasselli, A. | Tortorella, M D. | Williams, J M. | Alpha/beta structure | Central five stranded beta-sheet | Cleavage on pair of basic residue | Disulfide bond | Extracellular matrix | Glycoprotein | Hydrolase | Metal-binding | Metalloprotease | Protease | Secreted | Zymogen