3ig6
From Proteopedia
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===Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex=== | ===Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex=== | ||
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==See Also== | ==See Also== | ||
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==Reference== | ==Reference== |
Revision as of 10:15, 26 July 2012
Contents |
Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Template:ABSTRACT PUBMED 19703768
About this Structure
3ig6 is a 4 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- West CW, Adler M, Arnaiz D, Chen D, Chu K, Gualtieri G, Ho E, Huwe C, Light D, Phillips G, Pulk R, Sukovich D, Whitlow M, Yuan S, Bryant J. Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5712-5. Epub 2009 Aug 7. PMID:19703768 doi:10.1016/j.bmcl.2009.08.008
Categories: Homo sapiens | U-plasminogen activator | Adler, M. | Whitlow, M. | Blood coagulation | Disulfide bond | Egf-like domain | Fibrinolysis | Glycoprotein | Hydrolase | Kringle | Phosphoprotein | Plasminogen activation | Protease | S1 site inhibitor | Secreted | Selective | Serine protease | Structure-based drug design | Urokinase | Zymogen