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1y6k
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_1y6k| PDB=1y6k | SCENE= }} | {{STRUCTURE_1y6k| PDB=1y6k | SCENE= }} | ||
===Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain=== | ===Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain=== | ||
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{{ABSTRACT_PUBMED_15837194}} | {{ABSTRACT_PUBMED_15837194}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Graft-versus-host disease, protection against OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=124092 124092]], HIV-1, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=124092 124092]], Rheumatoid arthritis, progression of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=124092 124092]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1y6k]] is a 2 chain structure of [[Interleukin]] and [[Interleukin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6K OCA]. | |
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| + | ==See Also== | ||
| + | *[[Interleukin|Interleukin]] | ||
| + | *[[Interleukin receptor|Interleukin receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015837194</ref><ref group="xtra">PMID:016982608</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Jones, B C.]] | [[Category: Jones, B C.]] | ||
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[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Receptor complex]] | [[Category: Receptor complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:12:30 2009'' | ||
Revision as of 10:27, 26 July 2012
Contents |
Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain
Template:ABSTRACT PUBMED 15837194
About this Structure
1y6k is a 2 chain structure of Interleukin and Interleukin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yoon SI, Jones BC, Logsdon NJ, Walter MR. Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain. Structure. 2005 Apr;13(4):551-64. PMID:15837194 doi:10.1016/j.str.2005.01.016
- Yoon SI, Logsdon NJ, Sheikh F, Donnelly RP, Walter MR. Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex. J Biol Chem. 2006 Nov 17;281(46):35088-96. Epub 2006 Sep 18. PMID:16982608 doi:10.1074/jbc.M606791200
