1jcq
From Proteopedia
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===CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750=== | ===CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1jcq]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCQ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Farnesyltransferase|Farnesyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011687658</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Beese, L S.]] | [[Category: Beese, L S.]] | ||
[[Category: Casey, P J.]] | [[Category: Casey, P J.]] | ||
[[Category: Long, S B.]] | [[Category: Long, S B.]] | ||
| + | [[Category: 750]] | ||
[[Category: Caax]] | [[Category: Caax]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
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[[Category: Ftase]] | [[Category: Ftase]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
| - | [[Category: L-739 | + | [[Category: L-739]] |
[[Category: Peptidomimetic]] | [[Category: Peptidomimetic]] | ||
[[Category: Pft]] | [[Category: Pft]] | ||
[[Category: Pftase]] | [[Category: Pftase]] | ||
[[Category: Ra]] | [[Category: Ra]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Tumor regression]] | [[Category: Tumor regression]] | ||
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Revision as of 10:58, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750
Template:ABSTRACT PUBMED 11687658
About this Structure
1jcq is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS. The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12948-53. Epub 2001 Oct 30. PMID:11687658 doi:10.1073/pnas.241407898
Categories: Homo sapiens | Beese, L S. | Casey, P J. | Long, S B. | 750 | Caax | Cancer | Farnesyl protein transferase | Farnesyl transferase | Farnesyltransferase | Fpt | Ft | Ftase | Inhibitor | L-739 | Peptidomimetic | Pft | Pftase | Ra | Transferase | Tumor regression
