3bet
From Proteopedia
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[[Image:3bet.png|left|200px]] | [[Image:3bet.png|left|200px]] | ||
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{{STRUCTURE_3bet| PDB=3bet | SCENE= }} | {{STRUCTURE_3bet| PDB=3bet | SCENE= }} | ||
===Crystal structure of the human carbonic anhydrase II in complex with STX 641 at 1.85 angstroms resolution=== | ===Crystal structure of the human carbonic anhydrase II in complex with STX 641 at 1.85 angstroms resolution=== | ||
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{{ABSTRACT_PUBMED_18260615}} | {{ABSTRACT_PUBMED_18260615}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[3bet]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BET OCA]. | + | [[3bet]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BET OCA]. |
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+ | ==See Also== | ||
+ | *[[Carbonic anhydrase|Carbonic anhydrase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018260615</ref><ref group="xtra">PMID:003151019</ref><ref group="xtra">PMID:017181151</ref><references group="xtra"/> |
[[Category: Carbonate dehydratase]] | [[Category: Carbonate dehydratase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fiore, A Di.]] | [[Category: Fiore, A Di.]] | ||
[[Category: Simone, G De.]] | [[Category: Simone, G De.]] | ||
- | [[Category: Acetylation]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
- | [[Category: Zinc]] |
Revision as of 10:59, 26 July 2012
Contents |
Crystal structure of the human carbonic anhydrase II in complex with STX 641 at 1.85 angstroms resolution
Template:ABSTRACT PUBMED 18260615
About this Structure
3bet is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Leese MP, Jourdan FL, Gaukroger K, Mahon MF, Newman SP, Foster PA, Stengel C, Regis-Lydi S, Ferrandis E, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents. J Med Chem. 2008 Mar 13;51(5):1295-308. Epub 2008 Feb 9. PMID:18260615 doi:10.1021/jm701319c
- Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406
- Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151 doi:10.1021/jm060705x