3qbh
From Proteopedia
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{{STRUCTURE_3qbh| PDB=3qbh | SCENE= }} | {{STRUCTURE_3qbh| PDB=3qbh | SCENE= }} | ||
===Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors=== | ===Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors=== | ||
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{{ABSTRACT_PUBMED_21388807}} | {{ABSTRACT_PUBMED_21388807}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qbh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBH OCA]. | + | [[3qbh]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBH OCA]. |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021388807</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Rondeau, J M.]] | [[Category: Rondeau, J M.]] | ||
| + | [[Category: Enzyme inhibitor complex]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 11:09, 26 July 2012
Contents |
Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors
Template:ABSTRACT PUBMED 21388807
About this Structure
3qbh is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rueeger H, Rondeau JM, McCarthy C, Mobitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. Epub 2011 Feb 15. PMID:21388807 doi:10.1016/j.bmcl.2011.02.038
