2e9w
From Proteopedia
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[[Image:2e9w.png|left|200px]] | [[Image:2e9w.png|left|200px]] | ||
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{{STRUCTURE_2e9w| PDB=2e9w | SCENE= }} | {{STRUCTURE_2e9w| PDB=2e9w | SCENE= }} | ||
===Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)=== | ===Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)=== | ||
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{{ABSTRACT_PUBMED_17662946}} | {{ABSTRACT_PUBMED_17662946}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Gastrointestinal stromal tumor, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Germ cell tumors OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mast cell leukemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mastocytosis with associated hematologic disorder OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Piebaldism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Skin/hair/eye pigmentation 7, blond/brown hair OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=184745 184745]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2e9w]] is a 4 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9W OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017662946</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Growth factor cytokine]] | [[Category: Growth factor cytokine]] | ||
[[Category: Receptor tyrosine kinase]] | [[Category: Receptor tyrosine kinase]] | ||
| - | [[Category: Transferase | + | [[Category: Transferase-hormone complex]] |
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Revision as of 11:38, 26 July 2012
Contents |
Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
Template:ABSTRACT PUBMED 17662946
About this Structure
2e9w is a 4 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 2007 Jul 27;130(2):323-34. PMID:17662946 doi:http://dx.doi.org/10.1016/j.cell.2007.05.055
