2h5s
From Proteopedia
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[[Image:2h5s.png|left|200px]] | [[Image:2h5s.png|left|200px]] | ||
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{{STRUCTURE_2h5s| PDB=2h5s | SCENE= }} | {{STRUCTURE_2h5s| PDB=2h5s | SCENE= }} | ||
===SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase=== | ===SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase=== | ||
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{{ABSTRACT_PUBMED_17017804}} | {{ABSTRACT_PUBMED_17017804}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2h5s]] is a 1 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5S OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta-lactamase|Beta-lactamase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017017804</ref><references group="xtra"/> |
| - | [[Category: | + | [[Category: Beta-lactamase]] |
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
[[Category: Akker, F van den.]] | [[Category: Akker, F van den.]] | ||
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[[Category: Beta-lactamase inhibitor]] | [[Category: Beta-lactamase inhibitor]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
| - | + | [[Category: Hydrolase]] | |
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Revision as of 11:48, 26 July 2012
Contents |
SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase
Template:ABSTRACT PUBMED 17017804
About this Structure
2h5s is a 1 chain structure of Beta-lactamase with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.
See Also
Reference
- Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone. J Am Chem Soc. 2006 Oct 11;128(40):13235-42. PMID:17017804 doi:10.1021/ja063715w
