1mmk
From Proteopedia
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===Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine=== | ===Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine=== | ||
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{{ABSTRACT_PUBMED_14568534}} | {{ABSTRACT_PUBMED_14568534}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1mmk]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMK OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]] | ||
| + | *[[Tryptophan hydroxylase 1 with bound tryptophan|Tryptophan hydroxylase 1 with bound tryptophan]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014568534</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylalanine 4-monooxygenase]] | [[Category: Phenylalanine 4-monooxygenase]] | ||
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[[Category: Basket-arrangement]] | [[Category: Basket-arrangement]] | ||
[[Category: Ferrous iron]] | [[Category: Ferrous iron]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 11:50, 26 July 2012
Contents |
Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine
Template:ABSTRACT PUBMED 14568534
About this Structure
1mmk is a 1 chain structure of Phenylalanine hydroxylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Andersen OA, Stokka AJ, Flatmark T, Hough E. 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding. J Mol Biol. 2003 Oct 31;333(4):747-57. PMID:14568534
