3o5n
From Proteopedia
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[[Image:3o5n.png|left|200px]] | [[Image:3o5n.png|left|200px]] | ||
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{{STRUCTURE_3o5n| PDB=3o5n | SCENE= }} | {{STRUCTURE_3o5n| PDB=3o5n | SCENE= }} | ||
===Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders=== | ===Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders=== | ||
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{{ABSTRACT_PUBMED_21626699}} | {{ABSTRACT_PUBMED_21626699}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3o5n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA]. | + | [[3o5n]] is a 8 chain structure of [[Shank protein]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA]. |
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| + | ==See Also== | ||
| + | *[[Shank protein|Shank protein]] | ||
==Reference== | ==Reference== | ||
Revision as of 11:51, 26 July 2012
Contents |
Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders
Template:ABSTRACT PUBMED 21626699
About this Structure
3o5n is a 8 chain structure of Shank protein with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Saupe J, Roske Y, Schillinger C, Kamdem N, Radetzki S, Diehl A, Oschkinat H, Krause G, Heinemann U, Rademann J. Discovery, Structure-Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain. ChemMedChem. 2011 May 27. doi: 10.1002/cmdc.201100094. PMID:21626699 doi:10.1002/cmdc.201100094
