2fk2
From Proteopedia
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{{STRUCTURE_2fk2| PDB=2fk2 | SCENE= }} | {{STRUCTURE_2fk2| PDB=2fk2 | SCENE= }} | ||
===Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(I)-bound=== | ===Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(I)-bound=== | ||
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{{ABSTRACT_PUBMED_17239395}} | {{ABSTRACT_PUBMED_17239395}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Alzheimer disease-1, APP-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Dutch type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Iowa type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2fk2]] is a 1 chain structure of [[Amyloid precursor protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FK2 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Amyloid precursor protein|Amyloid precursor protein]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017239395</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kong, G K.W.]] | [[Category: Kong, G K.W.]] | ||
[[Category: Parker, M W.]] | [[Category: Parker, M W.]] | ||
[[Category: Alpha-beta two-layered sandwich]] | [[Category: Alpha-beta two-layered sandwich]] | ||
| - | + | [[Category: Apoptosis]] | |
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Revision as of 12:28, 26 July 2012
Contents |
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(I)-bound
Template:ABSTRACT PUBMED 17239395
About this Structure
2fk2 is a 1 chain structure of Amyloid precursor protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kong GK, Adams JJ, Harris HH, Boas JF, Curtain CC, Galatis D, Masters CL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions. J Mol Biol. 2007 Mar 16;367(1):148-61. Epub 2006 Dec 21. PMID:17239395 doi:10.1016/j.jmb.2006.12.041
