3klh
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{{STRUCTURE_3klh| PDB=3klh | SCENE= }} | {{STRUCTURE_3klh| PDB=3klh | SCENE= }} | ||
===Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)=== | ===Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)=== | ||
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{{ABSTRACT_PUBMED_20852643}} | {{ABSTRACT_PUBMED_20852643}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3klh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLH OCA]. | + | [[3klh]] is a 6 chain structure of [[AZT-resistant HIV-1 reverse transcriptase]], [[Monoclonal Antibody]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLH OCA]. |
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| + | ==See Also== | ||
| + | *[[AZT-resistant HIV-1 reverse transcriptase|AZT-resistant HIV-1 reverse transcriptase]] | ||
| + | *[[Monoclonal Antibody|Monoclonal Antibody]] | ||
| + | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020852643</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: Sarafianos, S G.]] | [[Category: Sarafianos, S G.]] | ||
[[Category: Tu, X.]] | [[Category: Tu, X.]] | ||
| + | [[Category: Aid]] | ||
| + | [[Category: Azt]] | ||
| + | [[Category: Azt excision]] | ||
| + | [[Category: Azt resistance]] | ||
| + | [[Category: Azt resistance mutation]] | ||
| + | [[Category: Dna polymerase]] | ||
| + | [[Category: Dna-directed dna polymerase]] | ||
| + | [[Category: Hiv]] | ||
| + | [[Category: Hiv-1]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Multifunctional enzyme]] | ||
| + | [[Category: Nrti]] | ||
| + | [[Category: Nuclease]] | ||
| + | [[Category: Nucleoside inhibitor]] | ||
| + | [[Category: Nucleotide excision]] | ||
| + | [[Category: P51/p66]] | ||
| + | [[Category: Resistance mechanism]] | ||
| + | [[Category: Reverse transcriptase]] | ||
| + | [[Category: Rna-directed dna polymerase]] | ||
| + | [[Category: Rt]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-dna complex]] | ||
Revision as of 12:29, 26 July 2012
Contents |
Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)
Template:ABSTRACT PUBMED 20852643
About this Structure
3klh is a 6 chain structure of AZT-resistant HIV-1 reverse transcriptase, Monoclonal Antibody and Reverse transcriptase with sequence from Human immunodeficiency virus 1 and Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908