3gpw
From Proteopedia
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{{STRUCTURE_3gpw| PDB=3gpw | SCENE= }} | {{STRUCTURE_3gpw| PDB=3gpw | SCENE= }} | ||
===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand=== | ===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand=== | ||
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{{ABSTRACT_PUBMED_19678642}} | {{ABSTRACT_PUBMED_19678642}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3gpw]] is a 28 chain structure of [[Proteasome]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GPW OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proteasome|Proteasome]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019678642</ref><references group="xtra"/> |
[[Category: Proteasome endopeptidase complex]] | [[Category: Proteasome endopeptidase complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
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[[Category: Potts, C B.]] | [[Category: Potts, C B.]] | ||
[[Category: Cancer therapy]] | [[Category: Cancer therapy]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Immunology]] | [[Category: Immunology]] | ||
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[[Category: Time-dependent elimination of a defined leaving group]] | [[Category: Time-dependent elimination of a defined leaving group]] | ||
[[Category: Ubiquitin]] | [[Category: Ubiquitin]] | ||
| - | [[Category: Ubl conjugation]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 09:02:11 2009'' | ||
Revision as of 12:49, 26 July 2012
Contents |
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand
Template:ABSTRACT PUBMED 19678642
About this Structure
3gpw is a 28 chain structure of Proteasome with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Categories: Proteasome endopeptidase complex | Saccharomyces cerevisiae | Arthur, K A.M. | Groll, M. | Macherla, V R. | Manam, R R. | Potts, C B. | Cancer therapy | Hydrolase | Immunology | Isopeptide bond | Nucleus | Phosphoprotein | Protease | Proteasome | Threonine protease | Time-dependent elimination of a defined leaving group | Ubiquitin | Zymogen
