2rd8

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[[Image:2rd8.png|left|200px]]
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{{STRUCTURE_2rd8| PDB=2rd8 | SCENE= }}
{{STRUCTURE_2rd8| PDB=2rd8 | SCENE= }}
===Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195===
===Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195===
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{{ABSTRACT_PUBMED_18370400}}
{{ABSTRACT_PUBMED_18370400}}
==About this Structure==
==About this Structure==
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2RD8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RD8 OCA].
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[[2rd8]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RD8 OCA].
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==See Also==
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*[[Thymidylate synthase|Thymidylate synthase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18370400</ref><references group="xtra"/>
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<ref group="xtra">PMID:018370400</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Nucleotide biosynthesis]]
[[Category: Nucleotide biosynthesis]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:28:43 2009''
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Revision as of 12:52, 26 July 2012

Template:STRUCTURE 2rd8

Contents

Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195

Template:ABSTRACT PUBMED 18370400

About this Structure

2rd8 is a 2 chain structure of Thymidylate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Gibson LM, Lovelace LL, Lebioda L. The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195. Biochemistry. 2008 Apr 22;47(16):4636-43. Epub 2008 Mar 28. PMID:18370400 doi:10.1021/bi7019386

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