3f3v

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[[Image:3f3v.png|left|200px]]
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{{STRUCTURE_3f3v| PDB=3f3v | SCENE= }}
{{STRUCTURE_3f3v| PDB=3f3v | SCENE= }}
===Kinase domain of cSrc in complex with inhibitor RL45 (Type II)===
===Kinase domain of cSrc in complex with inhibitor RL45 (Type II)===
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{{ABSTRACT_PUBMED_19462975}}
{{ABSTRACT_PUBMED_19462975}}
==About this Structure==
==About this Structure==
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3F3V is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3V OCA].
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[[3f3v]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3V OCA].
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==See Also==
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*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19462975</ref><references group="xtra"/>
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<ref group="xtra">PMID:019462975</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Rauh, D.]]
[[Category: Rauh, D.]]
[[Category: Allosteric]]
[[Category: Allosteric]]
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[[Category: Alternative splicing]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Dfg-out]]
[[Category: Dfg-out]]
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[[Category: Type ii]]
[[Category: Type ii]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:47:33 2009''
 

Revision as of 12:52, 26 July 2012

Template:STRUCTURE 3f3v

Contents

Kinase domain of cSrc in complex with inhibitor RL45 (Type II)

Template:ABSTRACT PUBMED 19462975

About this Structure

3f3v is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  • Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928

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