1yw9

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Template:STRUCTURE 1yw9

Contents

h-MetAP2 complexed with A849519

Template:ABSTRACT PUBMED 16789740

About this Structure

1yw9 is a 1 chain structure of Aminopeptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sheppard GS, Wang J, Kawai M, Fidanze SD, BaMaung NY, Erickson SA, Barnes DM, Tedrow JS, Kolaczkowski L, Vasudevan A, Park DC, Wang GT, Sanders WJ, Mantei RA, Palazzo F, Tucker-Garcia L, Lou P, Zhang Q, Park CH, Kim KH, Petros A, Olejniczak E, Nettesheim D, Hajduk P, Henkin J, Lesniewski R, Davidsen SK, Bell RL. Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J Med Chem. 2006 Jun 29;49(13):3832-49. PMID:16789740 doi:10.1021/jm0601001

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OCA

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