3bvb

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[[Image:3bvb.png|left|200px]]
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{{STRUCTURE_3bvb| PDB=3bvb | SCENE= }}
{{STRUCTURE_3bvb| PDB=3bvb | SCENE= }}
===Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir===
===Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir===
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{{ABSTRACT_PUBMED_18281688}}
{{ABSTRACT_PUBMED_18281688}}
==About this Structure==
==About this Structure==
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[[3bvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVB OCA].
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[[3bvb]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVB OCA].
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==See Also==
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*[[Virus protease|Virus protease]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18281688</ref><ref group="xtra">PMID:12933791</ref><ref group="xtra">PMID:16277992</ref><references group="xtra"/>
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<ref group="xtra">PMID:018281688</ref><ref group="xtra">PMID:012933791</ref><ref group="xtra">PMID:016277992</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Capsid maturation]]
[[Category: Capsid maturation]]
[[Category: Core protein]]
[[Category: Core protein]]
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[[Category: Cytoplasm]]
 
[[Category: D25n]]
[[Category: D25n]]
[[Category: Dna integration]]
[[Category: Dna integration]]
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[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
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[[Category: Zinc]]
 
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 13:02, 26 July 2012

Image:3bvb.png

Template:STRUCTURE 3bvb

Contents

Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir

Template:ABSTRACT PUBMED 18281688

About this Structure

3bvb is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Sayer JM, Liu F, Ishima R, Weber IT, Louis JM. Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease. J Biol Chem. 2008 May 9;283(19):13459-70. Epub 2008 Feb 15. PMID:18281688 doi:10.1074/jbc.M708506200
  • Ishima R, Torchia DA, Lynch SM, Gronenborn AM, Louis JM. Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem. 2003 Oct 31;278(44):43311-9. Epub 2003 Aug 21. PMID:12933791 doi:http://dx.doi.org/10.1074/jbc.M307549200
  • Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095

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