2h15

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[[Image:2h15.png|left|200px]]
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{{STRUCTURE_2h15| PDB=2h15 | SCENE= }}
{{STRUCTURE_2h15| PDB=2h15 | SCENE= }}
===Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II===
===Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II===
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{{ABSTRACT_PUBMED_17125255}}
{{ABSTRACT_PUBMED_17125255}}
==About this Structure==
==About this Structure==
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2H15 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H15 OCA].
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[[2h15]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H15 OCA].
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==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17125255</ref><references group="xtra"/>
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<ref group="xtra">PMID:017125255</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Winum, J Y.]]
[[Category: Winum, J Y.]]
[[Category: Carbonic anhydrase]]
[[Category: Carbonic anhydrase]]
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[[Category: Crystal structure]]
 
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:50:15 2009''
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Revision as of 13:20, 26 July 2012

Template:STRUCTURE 2h15

Contents

Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II

Template:ABSTRACT PUBMED 17125255

About this Structure

2h15 is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Winum JY, Temperini C, El Cheikh K, Innocenti A, Vullo D, Ciattini S, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue. J Med Chem. 2006 Nov 30;49(24):7024-31. PMID:17125255 doi:10.1021/jm060807n

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