1hvy
From Proteopedia
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{{STRUCTURE_1hvy| PDB=1hvy | SCENE= }} | {{STRUCTURE_1hvy| PDB=1hvy | SCENE= }} | ||
===Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation=== | ===Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation=== | ||
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{{ABSTRACT_PUBMED_11329255}} | {{ABSTRACT_PUBMED_11329255}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1hvy]] is a 4 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HVY OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011329255</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
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[[Category: Raltitrexed]] | [[Category: Raltitrexed]] | ||
[[Category: Tomudex]] | [[Category: Tomudex]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 13:43, 26 July 2012
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| 1hvy, resolution 1.90Å () | |||||||||
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| Ligands: | , , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Thymidylate synthase, with EC number 2.1.1.45 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
Template:ABSTRACT PUBMED 11329255
About this Structure
1hvy is a 4 chain structure of Thymidylate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L. Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. Biochemistry. 2001 Feb 20;40(7):1897-902. PMID:11329255
