3mpt
From Proteopedia
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Revision as of 13:47, 26 July 2012
Contents |
Crystal structure of P38 kinase in complex with a pyrrole-2-carboxamide inhibitor
Template:ABSTRACT PUBMED 20570148
About this Structure
3mpt is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Down K, Bamborough P, Alder C, Campbell A, Christopher JA, Gerelle M, Ludbrook S, Mallett D, Mellor G, Miller DD, Pearson R, Ray K, Solanke Y, Somers D. The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38alpha MAP kinase. Bioorg Med Chem Lett. 2010 Jul 1;20(13):3936-40. Epub 2010 May 10. PMID:20570148 doi:10.1016/j.bmcl.2010.05.011