1tqf
From Proteopedia
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===Crystal structure of human Beta secretase complexed with inhibitor=== | ===Crystal structure of human Beta secretase complexed with inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1tqf]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQF OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015566281</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Bace]] | [[Category: Bace]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:27:15 2009'' | ||
Revision as of 14:10, 26 July 2012
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| 1tqf, resolution 1.80Å () | |||||||||
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| Ligands: | |||||||||
| Gene: | BACE1, BACE (Homo sapiens) | ||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal structure of human Beta secretase complexed with inhibitor
Template:ABSTRACT PUBMED 15566281
About this Structure
1tqf is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, Munshi S, Kuo L, Makara GM, Annis DA, Tadikonda PK, Nash HM, Vacca JP, Wang T. Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. J Med Chem. 2004 Dec 2;47(25):6117-9. PMID:15566281 doi:10.1021/jm049388p
Categories: Homo sapiens | Memapsin 2 | Chen, Z. | Kuo, L. | Munshi, S. | Aspartyl protease | Bace | Hydrolase
