3k3j

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Image:3k3j.png

Template:STRUCTURE 3k3j

Contents

P38alpha bound to novel DFG-out compound PF-00416121

Template:ABSTRACT PUBMED 19843080

About this Structure

3k3j is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Tecle H, Feru F, Liu H, Kuhn C, Rennie G, Morris M, Shao J, Cheng AC, Gikunju D, Miret J, Coli R, Xi SH, Clugston SL, Low S, Kazmirski S, Ding YH, Cao Q, Johnson TL, Deshmukh GD, DiNitto JP, Wu JC, English JM. The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay. Chem Biol Drug Des. 2009 Dec;74(6):547-59. Epub 2009 Oct 20. PMID:19843080 doi:10.1111/j.1747-0285.2009.00884.x

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OCA

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