2cib
From Proteopedia
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[[Image:2cib.png|left|200px]] | [[Image:2cib.png|left|200px]] | ||
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{{STRUCTURE_2cib| PDB=2cib | SCENE= }} | {{STRUCTURE_2cib| PDB=2cib | SCENE= }} | ||
===HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS=== | ===HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS=== | ||
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{{ABSTRACT_PUBMED_17846131}} | {{ABSTRACT_PUBMED_17846131}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[Cytochrome P450|Cytochrome P450]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017846131</ref><references group="xtra"/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Sterol 14-demethylase]] | [[Category: Sterol 14-demethylase]] | ||
Revision as of 14:42, 26 July 2012
Contents |
HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS
Template:ABSTRACT PUBMED 17846131
About this Structure
2cib is a 1 chain structure of Cytochrome P450 with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Altekoster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR. Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. Antimicrob Agents Chemother. 2007 Nov;51(11):3915-23. Epub 2007 Sep 10. PMID:17846131 doi:10.1128/AAC.00311-07
Categories: Mycobacterium tuberculosis | Sterol 14-demethylase | Kim, Y. | Kries, J P.Von. | Podust, L M. | Waterman, M R. | Yermalitskaya, L V. | Heme | Heme lipid synthesis | Metal-binding | Monooxygenase | Nadp | Oxidoreductase | Protein-inhibitor complex | Steroid biosynthesis | Sterol biosynthesis
