3fc1
From Proteopedia
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[[Image:3fc1.png|left|200px]] | [[Image:3fc1.png|left|200px]] | ||
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{{STRUCTURE_3fc1| PDB=3fc1 | SCENE= }} | {{STRUCTURE_3fc1| PDB=3fc1 | SCENE= }} | ||
===Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor=== | ===Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Mitogen-activated protein kinase]] | + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016302819</ref><ref group="xtra">PMID:011585447</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
[[Category: Bellon, S.]] | [[Category: Bellon, S.]] | ||
[[Category: Jacobs, M D.]] | [[Category: Jacobs, M D.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Kinase inhibitor]] | [[Category: Kinase inhibitor]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 14:45, 26 July 2012
Contents |
Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor
Template:ABSTRACT PUBMED 16302819
About this Structure
3fc1 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Pearlman DA. Evaluating the molecular mechanics poisson-boltzmann surface area free energy method using a congeneric series of ligands to p38 MAP kinase. J Med Chem. 2005 Dec 1;48(24):7796-807. PMID:16302819 doi:10.1021/jm050306m
- Pearlman DA, Charifson PS. Are free energy calculations useful in practice? A comparison with rapid scoring functions for the p38 MAP kinase protein system. J Med Chem. 2001 Oct 11;44(21):3417-23. PMID:11585447
