1mu6
From Proteopedia
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[[Image:1mu6.png|left|200px]] | [[Image:1mu6.png|left|200px]] | ||
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{{STRUCTURE_1mu6| PDB=1mu6 | SCENE= }} | {{STRUCTURE_1mu6| PDB=1mu6 | SCENE= }} | ||
===Crystal Structure of Thrombin in Complex with L-378,622=== | ===Crystal Structure of Thrombin in Complex with L-378,622=== | ||
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{{ABSTRACT_PUBMED_12570369}} | {{ABSTRACT_PUBMED_12570369}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1mu6]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU6 OCA]. | + | [[1mu6]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU6 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012570369</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-blood clotting complex]] |
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Hydrolase-inhibitor complex]] | ||
Revision as of 14:56, 26 July 2012
Contents |
Crystal Structure of Thrombin in Complex with L-378,622
Template:ABSTRACT PUBMED 12570369
About this Structure
1mu6 is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369 doi:http://dx.doi.org/10.1021/jm020311f
Categories: Homo sapiens | Thrombin | Barrow, J C. | Bohn, D. | Burgey, C S. | Chen, Z. | Clayton, F C. | Coburn, C A. | Cook, J J. | Detwiler, T J. | Dorsey, B D. | Gardell, S J. | Holahan, M A. | Krueger, J A. | Kuo, L. | Leonard, Y M. | Lewis, S D. | Lucas, B J. | Lyle, E A. | Lyle, T A. | Lynch, J J. | McDonough, C M. | McMasters, D R. | Miller-Stein, C. | Robinson, K A. | Sanders, W M. | Sanderson, P E. | Shafer, J A. | Singh, R. | Sitko, G R. | Stranieri, M T. | Vacca, J P.J. | Wallace, A A. | White, R B. | Williams, P D. | Wong, B. | Yan, Y. | Blood clotting | Hydrolase | Hydrolase-blood clotting complex | Hydrolase-hydrolase inhibitor complex | Hydrolase-inhibitor complex
