3o56

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[[Image:3o56.jpg|left|200px]]
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{{STRUCTURE_3o56| PDB=3o56 | SCENE= }}
{{STRUCTURE_3o56| PDB=3o56 | SCENE= }}
===Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor===
===Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor===
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{{ABSTRACT_PUBMED_20732811}}
{{ABSTRACT_PUBMED_20732811}}
==About this Structure==
==About this Structure==
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[[3o56]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O56 OCA].
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[[3o56]] is a 1 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O56 OCA].
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==See Also==
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*[[Phosphodiesterase|Phosphodiesterase]]
==Reference==
==Reference==

Revision as of 15:06, 26 July 2012

Template:STRUCTURE 3o56

Contents

Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor

Template:ABSTRACT PUBMED 20732811

About this Structure

3o56 is a 1 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Mitchell CJ, Ballantine SP, Coe DM, Cook CM, Delves CJ, Dowle MD, Edlin CD, Hamblin JN, Holman S, Johnson MR, Jones PS, Keeling SE, Kranz M, Lindvall M, Lucas FS, Neu M, Solanke YE, Somers DO, Trivedi NA, Wiseman JO. Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5803-6. Epub 2010 Aug 5. PMID:20732811 doi:10.1016/j.bmcl.2010.07.136

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