1w9s
From Proteopedia
(New page: 200px<br /> <applet load="1w9s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w9s, resolution 1.59Å" /> '''STRUCTURE OF A BETA...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1W9S is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]] with NA and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W9S OCA]]. | + | 1W9S is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]] with NA and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W9S OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: lectin]] | [[Category: lectin]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:57:33 2007'' |
Revision as of 11:52, 30 October 2007
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STRUCTURE OF A BETA-1,3-GLUCAN BINDING CBM6 FROM BACILLUS HALODURANS
Overview
Enzymes that hydrolyze insoluble complex polysaccharide structures contain, non-catalytic carbohydrate binding modules (CBMS) that play a pivotal role, in the action of these enzymes against recalcitrant substrates. Family 6, CBMs (CBM6s) are distinct from other CBM families in that these protein, modules contain multiple distinct ligand binding sites, a feature that, makes CBM6s particularly appropriate receptors for the beta-1,3-glucan, laminarin, which displays an extended U-shaped conformation. To, investigate the mechanism by which family 6 CBMs recognize laminarin, we, report the biochemical and structural properties of a CBM6 (designated, BhCBM6) that is located in an enzyme, which is shown, in this work, to, display beta-1,3-glucanase activity. BhCBM6 binds, ... [(full description)]
About this Structure
1W9S is a [Single protein] structure of sequence from [Bacillus halodurans] with NA and GOL as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Family 6 carbohydrate binding modules recognize the non-reducing end of beta-1,3-linked glucans by presenting a unique ligand binding surface., van Bueren AL, Morland C, Gilbert HJ, Boraston AB, J Biol Chem. 2005 Jan 7;280(1):530-7. Epub 2004 Oct 22. PMID:15501830
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