This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1eo1
From Proteopedia
(New page: 200px<br /><applet load="1eo1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1eo1" /> '''Solution structure of hypothetical protein M...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1eo1.gif|left|200px]]<br /><applet load="1eo1" size=" | + | [[Image:1eo1.gif|left|200px]]<br /><applet load="1eo1" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1eo1" /> | caption="1eo1" /> | ||
'''Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum'''<br /> | '''Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The solution structure of MTH1175, a 124-residue protein from the archaeon | + | The solution structure of MTH1175, a 124-residue protein from the archaeon Methanobacterium thermoautotrophicum has been determined by NMR spectroscopy. MTH1175 is part of a family of conserved hypothetical proteins (COG1433) with unknown functions which contains multiple paralogs from all complete archaeal genomes and the archaeal gene-rich bacterium Thermotoga maritima. Sequence similarity indicates this protein family may be related to the nitrogen fixation proteins NifB and NifX. MTH1175 adopts an alpha/beta topology with a single mixed beta-sheet, and contains two flexible loops and an unstructured C-terminal tail. The fold resembles that of Ribonuclease H and similar proteins, but differs from these in several respects, and is not likely to have a nuclease activity. |
==About this Structure== | ==About this Structure== | ||
| - | 1EO1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http:// | + | 1EO1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EO1 OCA]. |
==Reference== | ==Reference== | ||
| Line 13: | Line 13: | ||
[[Category: Methanothermobacter thermautotrophicus]] | [[Category: Methanothermobacter thermautotrophicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Arrowsmith, C | + | [[Category: Arrowsmith, C H.]] |
| - | [[Category: Cort, J | + | [[Category: Cort, J R.]] |
| - | [[Category: Kennedy, M | + | [[Category: Kennedy, M A.]] |
| - | [[Category: NESG, Northeast | + | [[Category: NESG, Northeast Structural Genomics Consortium.]] |
[[Category: mixed a/b protein]] | [[Category: mixed a/b protein]] | ||
[[Category: mixed beta sheet]] | [[Category: mixed beta sheet]] | ||
| Line 27: | Line 27: | ||
[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:29:45 2008'' |
Revision as of 10:29, 21 February 2008
|
Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum
Overview
The solution structure of MTH1175, a 124-residue protein from the archaeon Methanobacterium thermoautotrophicum has been determined by NMR spectroscopy. MTH1175 is part of a family of conserved hypothetical proteins (COG1433) with unknown functions which contains multiple paralogs from all complete archaeal genomes and the archaeal gene-rich bacterium Thermotoga maritima. Sequence similarity indicates this protein family may be related to the nitrogen fixation proteins NifB and NifX. MTH1175 adopts an alpha/beta topology with a single mixed beta-sheet, and contains two flexible loops and an unstructured C-terminal tail. The fold resembles that of Ribonuclease H and similar proteins, but differs from these in several respects, and is not likely to have a nuclease activity.
About this Structure
1EO1 is a Single protein structure of sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.
Reference
NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum., Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA, J Struct Funct Genomics. 2000;1(1):15-25. PMID:12836677
Page seeded by OCA on Thu Feb 21 12:29:45 2008
Categories: Methanothermobacter thermautotrophicus | Single protein | Arrowsmith, C H. | Cort, J R. | Kennedy, M A. | NESG, Northeast Structural Genomics Consortium. | Mixed a/b protein | Mixed beta sheet | Nesg | Northeast structural genomics consortium | Protein structure initiative | Psi | Strand order 321456 | Strands 2 and 6 antiparallel to rest. | Structural genomics
