This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2bdy
From Proteopedia
(Difference between revisions)
m (Protected "2bdy" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:2bdy.png|left|200px]] | [[Image:2bdy.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2bdy", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2bdy| PDB=2bdy | SCENE= }} | {{STRUCTURE_2bdy| PDB=2bdy | SCENE= }} | ||
===thrombin in complex with inhibitor=== | ===thrombin in complex with inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16290930}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16290930 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16290930}} | {{ABSTRACT_PUBMED_16290930}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2bdy]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BDY OCA]. | + | [[2bdy]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BDY OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016290930</ref><references group="xtra"/> |
| + | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 31: | Line 22: | ||
[[Category: Complex structure]] | [[Category: Complex structure]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
Revision as of 17:19, 26 July 2012
Contents |
thrombin in complex with inhibitor
Template:ABSTRACT PUBMED 16290930
About this Structure
2bdy is a 2 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hanessian S, Therrien E, van Otterlo WA, Bayrakdarian M, Nilsson I, Fjellstrom O, Xue Y. Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1032-6. Epub 2005 Nov 15. PMID:16290930 doi:10.1016/j.bmcl.2005.10.082
