2h8h
From Proteopedia
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[[Image:2h8h.png|left|200px]] | [[Image:2h8h.png|left|200px]] | ||
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{{STRUCTURE_2h8h| PDB=2h8h | SCENE= }} | {{STRUCTURE_2h8h| PDB=2h8h | SCENE= }} | ||
===Src kinase in complex with a quinazoline inhibitor=== | ===Src kinase in complex with a quinazoline inhibitor=== | ||
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{{ABSTRACT_PUBMED_17064066}} | {{ABSTRACT_PUBMED_17064066}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2h8h]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8H OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017064066</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Rowsell, S.]] | [[Category: Rowsell, S.]] | ||
[[Category: Src kinase]] | [[Category: Src kinase]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 17:32, 26 July 2012
Contents |
Src kinase in complex with a quinazoline inhibitor
Template:ABSTRACT PUBMED 17064066
About this Structure
2h8h is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hennequin LF, Allen J, Breed J, Curwen J, Fennell M, Green TP, Lambert-van der Brempt C, Morgentin R, Norman RA, Olivier A, Otterbein L, Ple PA, Warin N, Costello G. N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J Med Chem. 2006 Nov 2;49(22):6465-88. PMID:17064066 doi:10.1021/jm060434q
